John Stamos and Lori Loughlin performed one among TV's best {couples} and their off-screen relationship has been simply as candy.
Stamos and Loughlin linked previous to their time on Full Home, even occurring a date to Disneyland once they had been younger adults. Whereas it didn't work out on the time, they reconnected once they joined the forged of Full Home. Stamos starred as Uncle Jesse whereas Loughlin performed his love curiosity, Aunt Becky.
A romance didn't blossom for Loughlin and Stamos because the actress was together with her first husband, Michael Burns. Loughlin and Burns had been married from 1989 to 1996. The next 12 months, Loughlin moved on with Mossimo Giannulli. Stamos, for his half, was married to Rebecca Romijn from 1998 to 2005 earlier than he discovered the one with Caitlin McHugh.
“We did have some off timing,” Stamos mentioned in a 2013 interview with the Huffington Publish. “However no disrespect to her household and her husband now, I might say that she might be the one which bought away.”
Whereas a love connection didn't type for Stamos and Loughlin, the pair cultivated a powerful friendship that has lasted a long time. Following Loughlin's divorce from Giannulli in September 2025, Stamos even voiced his assist for his former costar.
Hold scrolling for Stamos and Loughlin's greatest quotes about their relationship:
Why a Romance Didn't Work Out

Lori Loughlin, John Stamos Bob D'Amico /Walt Disney Tv by way of Getty Photos
Throughout a 2013 interview with the Huffington Publish, Loughlin opened up about why she and Stamos by no means dated in actual life.
“We had been nice buddies … and we've chemistry. I used to be really married on the time I used to be doing the present after which I bought divorced, and once I bought divorced he met Rebecca and he bought married,” she recalled. “So our timing was simply actually off so I don't suppose it actually even entered our minds that it will be one thing extra.”
That very same 12 months, Stamos spoke to the outlet to name Loughlin “the one who bought away.”
“She's one among my dearest buddies, and that's adequate,” he confessed. “However I actually do adore her.”
After listening to Stamos' remarks, Loughlin advised Yahoo's Every day Shot that it “was very good of him to say that.”
Lacking His Wedding ceremony
When Loughlin couldn't attend Stamos' marriage ceremony to McHugh as a consequence of a piece dedication, she solely advised Us Weekly that she despatched one thing particular to the pleased couple.
“I despatched flowers and I used to be actually bummed that I already had plans,” she advised Us. “However I'm so pleased for John, by the way in which. I'm so pleased he's going to be a dad. He's going to be a terrific dad. He's all the time been good with children. And Caitlin is simply the best woman. She's so good for him. I'm pleased to see that he's lastly discovered love.”
Being There for Every Different

Lori Loughlin, John Stamos JB Lacroix/WireImage
In Stamos' 2023 memoir, If You Would Have Informed Me, the actor opened up about his bond with Loughlin.
“She's my Sandra Dee from Grease, the great woman with a form coronary heart who all the time makes me really feel upbeat once I'm round her,” he wrote. “She's one of many few girls I've spent day after day with and nonetheless all the time sit up for seeing her once more. I do know what makes her chuckle, we get one another and we've the kind of true friendship that's presupposed to be the muse of a terrific, lasting relationship.”
Stamos shared that Loughlin has been a “cherished buddy” all through his life as they've each struggled with robust moments of their lives.
“We've weathered storms collectively and stood by one another's sides, regardless of life‘s hurdles. We've seen one another at our worst,” he penned. “I've witnessed moments the place giving up may've been the best means out for Lori. She may have shifted the blame and let her household, marriage, and life crumble. However she didn't. Irrespective of how arduous she was hit, how determined everybody was to cancel her and throw her in with the pile of brutal criminals, she stood quick, defending her daughters from the mud hurled at them day after day after day.”
Having Her Again
One month after information broke of Loughlin's cut up from Giannulli, Stamos shared his assist for his longtime buddy.
“40 years I've identified her,” Stamos mentioned throughout an October 2025 episode of the “Good Guys” podcast. “You may see by individuals after just a few years. This girl's a saint. I'm simply heartbroken for her proper now.”
Stamos additionally didn't maintain again his ideas about Giannulli and blamed him for the twosome's involvement within the faculty admissions scandal.
“I actually tried to be there for her throughout this time and likewise with the school scandal … I'm not going to debate whether or not she had a lot to do with it or not,” he mentioned. “I do know she didn't.”
