Search for bulbous fingertip enlargement, nails curving downward, a sharper nail‑fold angle, heat, and “floating” nails; this will accompany non‑small‑cell lung most cancers and could also be a part of HPOA.
Why it issues: Clubbing displays irregular vascular and connective tissue modifications on the digits, doubtless mediated by components resembling VEGF, and warrants analysis for thoracic illness.
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